Author: Vector staff

Scientific journey from ocean waves to brain waves yields BRAIN grant

From a series on researchers and innovators at Boston Children’s Hospital

For a researcher who started her career studying sound waves in the ocean, winning a BRAIN Early Concept Grant for Exploratory Research (EAGER) grant from the National Science Foundation is a pretty impressive accomplishment. The grant, part of President Obama’s BRAIN Initiative to advance transformative research on the brain, affirms Caterina Stamoulis’s shift of focus from the depths of the sea to the depths of the brain. She’s not alone: the neuroscience field is attracting scientists from the physical sciences who bring a fresh perspective to the analysis of brain signals.

Today, Stamoulis, who holds a PhD in underwater acoustics from MIT, holds faculty appointments in radiology and neurology and at Boston Children’s.

What are the goals of your BRAIN project?

We aim to characterize age-related changes in the brain’s rhythmic activity (neural oscillations) during the first three years of life. The brain changes at a remarkable pace during this period. It is also a period when several neurodevelopmental disorders, such as autism spectrum disorders (ASD), manifest themselves.

To understand how these disorders affect brain activity and consequently cognitive function, we first need to better understand how fundamental aspects of brain activity, such as neural oscillations, change with age in the typically developing brain. To characterize the trajectories of these oscillations, we will use novel computational tools and large volumes of human electrophysiological (EEG) data.

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CEO panel: Making health care work for children

Last in a series of videotaped sessions from Boston Children’s Hospital’s Global Pediatric Innovation Summit + Awards 2014. View Vector’s full coverage of the Summit.

Children’s hospitals face the challenges of a relatively small patient population, regulatory barriers and care outcomes that may not be measurable for decades. But challenges also bring opportunities. This fall 2014 panel, hosted by Children’s Hospital Association President and CEO Mark Wietecha, gathered CEOs from some of the world’s most respected pediatric hospitals:

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15 health care predictions for 2015

healthcare predictions
2014 continued to see massive evolution in health care—from digital health innovations to the maturation of technologies in genomics, genome editing and regenerative medicine to the configuration of the health care system itself. We asked leaders from the clinical, research and business corners of Boston Children’s Hospital to weigh in with their forecasts for 2015. Click “Full story” for them all, or jump to:
The consumer movement in health care
Evolving care models
Genomics in medicine
Stem cell therapeutics
Therapeutic development
New technology
Biomedical research

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Health care in a hyper-connected world: Cisco’s Carlos Dominguez

Part of a series of videotaped sessions from Boston Children’s Hospital’s Global Pediatric Innovation Summit + Awards 2014.

Carlos Dominguez is a technology evangelist, social media maven and a Senior VP at the IT company Cisco Systems, Inc. In this animated keynote presentation, he poses the question: how can health care organizations innovate in a world transformed by the web, social media and mobile phones, where “distance is dead,” knowledge is totally democratized and kids are born digital? Innovation isn’t luck, he contends, it’s a discipline that should work its way into an organization’s DNA.

Click here for full coverage of the Global Pediatric Innovation Summit. Videos are also available on YouTube.

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A teen’s journey: Developing a diagnostic test for pancreatic cancer

Part of a continuing series of videotaped sessions at Boston Children’s Hospital’s recent Global Pediatric Innovation Summit + Awards 2014.

At age 13, Jack Andraka lost a family friend to pancreatic cancer. At age 15, he developed a diagnostic test for pancreatic cancer that early findings suggest is highly accurate. In this session, Andraka describes his journey, the Johns Hopkins professor who took him on, his fascination with carbon nanotubes and how open access to scientific journals can help people around the world create solutions to problems. The diagnostic itself is in the early phases of testing.

Read our day-of coverage of this session along with full coverage of the Global Pediatric Innovation Summit. Our video coverage is also available on YouTube.

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Rare disease: The path less chosen

Part of a continuing series of videotaped sessions at Boston Children’s Hospital’s recent Global Pediatric Innovation Summit + Awards 2014.

Rare diseases offer a lot of opportunity for gene discovery, but getting a drug to market presents many challenges, and costs per patient are high. This 50-minute session explored this complicated landscape from multiple angles. The panelists:

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At this pediatric ‘shark tank,’ the children win

Part of a continuing series of videotaped sessions at Boston Children’s Hospital’s recent Global Pediatric Innovation Summit + Awards 2014.

It was an ABC “Shark Tank” lover’s dream: At this pediatric Innovation Tank moderated by Daymond John, venture capitalists and clinicians fielded pitches from innovators looking to advance their care solution before a packed audience. The contenders:

  • A soft sleeve and wrap to keep catheter central lines in place, created by a parent
  • A handheld device that cleanses central line hubs, freeing up clinicians’ time
  • A mobile weight-loss program for kids and teenagers, designed to teach healthy habits

We won’t disclose the results–you’ll just have to watch the proceedings–but as emcee Bruce Zetter, PhD, of Boston Children’s put it, “The children win.”

Stay tuned as we post more sessions from the Pediatric Innovation Summit (also available on YouTube) and read our blog coverage.

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IBM’s Watson at work: Transforming health care

Part of a continuing series of videotaped sessions at Boston Children’s Hospital’s recent Global Pediatric Innovation Summit + Awards 2014.

What’s IBM’s Watson been up to since winning Jeopardy? Among other things, it’s been trying to help doctors make decisions. “We live in an age of information overload,” says Mike Rhodin, Senior Vice President of the IBM Watson Group. “The challenge is to now turn that information into knowledge.”

Interestingly, most of the inquiries Rhodin received post-Jeopardy were from doctors, who were interested in the way Watson sorted and ranked possible answers. Here, Rhodin and Dan Cerutti, VP of Watson Commercialization, outline IBM’s vision to improve global health care through a technology platform called CarePlex:

Stay tuned as we post more sessions from the Pediatric Innovation Summit (also available on YouTube) and read our blog coverage.

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Megatrends in U.S. health care: Zeke Emanuel

Third in a series of videotaped sessions at Boston Children’s Hospital’s recent Global Pediatric Innovation Summit + Awards 2014.

Ezekiel “Zeke” Emanuel MD, PhD, former health advisor to President Barack Obama and current Vice Provost for Global Initiatives and Chair of the Department of Medical Ethics & Health Policy at University of Pennsylvania, has plenty to say about where health care is headed. Keynoting at the Global Pediatric Summit 2014, Zeke outlines six predictions and what academic medical centers and the larger industry will need to do to survive.

Stay tuned as we post more sessions from the Pediatric Innovation Summit (also available on YouTube) and read our blog coverage.

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A prescription for health care disruption: Fast Company’s Bill Taylor

Second in a series of videotaped sessions at Boston Children’s Hospital’s recent Global Pediatric Innovation Summit + Awards 2014.

Your first job as an innovator is to persuade your colleagues that playing it safe is the riskiest strategy of all, says Bill Taylor, Fast Company’s cofounder and founding editor. During his keynote address, “A Practically Radical Prescription for Health Care,” Taylor urged health care innovators to embrace change and look broadly to other fields–even the circus–for lessons.

He invoked what George Carlin called “vuja de”: The opposite of deja vu, it’s seeing a familiar thing in new way. “We learn and grow the most when we meet with people unlike us,” Taylor said.

Ask yourself, “What are we offering that is hard to come by?” Fill a need before other organizations even see it. It may be hidden in plain sight. Here’s Taylor’s talk in full:

Stay tuned as we post more sessions from the Pediatric Innovation Summit (also available on YouTube) and read our blog coverage.

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