Stories about: Innovation and Digital Health Accelerator

Lessons from the data: Applying machine learning for clinical decision support

machine learning clinical decision support

Mauricio Santillana, PhD, faculty member in the Computational Health Informatics Program at Boston Children’s Hospital, had an idea as he witnessed the volume of continuous real-time data generated in the pediatric intensive care unit (PICU). He realized that tapping the data on patients’ ever-changing vital signs, with the help of machine-learning algorithms, could support clinical decision-making and predict (and help head off) up-coming health issues.

He started a dialogue with the hospital’s Innovation & Digital Health Accelerator, and now collaborates closely with clinicians in the PICU to create machine-learning algorithms that can help them provide the highest level of care.

“It’s fairly recent that clinicians realized people with backgrounds in math and statistics can be very helpful in a clinical context,” says Santillana

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A 30-minute screening test for dyslexia?

dyslexia screening test
A dyslexia screening app in development could flag children at risk as early as age 4, when interventions are most effective.

Ten to 12 percent of school-aged children have dyslexia. It’s typically diagnosed in second or third grade, only after a child has struggled unsuccessfully at reading. As Nadine Gaab, PhD, of Boston Children’s Hospital puts it, diagnosis is primarily based upon a “wait-to-fail-approach.” And that comes along with considerable psychological damage and stigma.

“Late diagnosis of dyslexia very often leads to low self-esteem, depression and antisocial behavior,” she says. A much better time to look for early signs of dyslexia would be kindergarten or first grade. With early intervention, many children can attain an average reading ability.

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2017 Innovators’ Showcase spotlights healthcare decision support

2017 Innovator's Showcase Boston Children's Hospital

Healthcare innovations will be on display next week — April 12 — at Boston Children’s Hospital’s Innovation & Digital Health Accelerator’s annual showcase. The event, from 3:30 to 5:30 p.m., will be kicked off by a discussion on clinical decision support with Doug Perrin, a bioengineer/computer scientist in Cardiac Surgery at Boston Children’s and Garry Steil, who is developing a glucose control technology for diabetes patients at the hospital.

Exhibits, demos and mingling will take place in the Patient Entertainment Center off the main hospital lobby (300 Longwood Avenue, Boston).

Among the roughly 20 apps, ventures and technologies on display:

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Designing from the bottom up: Guiding healthcare stakeholders through ideation

healthcare co-design

At a recent event, Michelle Domey, mother of a child with special health care needs, found herself sharing her experience with a design expert, describing recent telehealth appointments at Boston Children’s Hospital. “My son feels like he’s having a private appointment, even though I’m sitting next to him, and his doctor is miles away,” she reflected. “Who thought that was possible through a tablet or a computer?”

As adult patients nodded in agreement, the group began to think about how to leverage Michelle’s experience to design support systems for kids with special health care needs. A software engineer expanded Michelle’s comment into a vision of the classroom of the future — a learning environment fully equipped with remote learning solutions for children with special health care needs, and environmental sensors for children with severe food allergies and health risks. The Olin College Co-Design for Better Health Innovation Lab was well underway.

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Developing a startup: bringing your healthcare innovation to market

a digital health startup

Sixth and last in an on-going series of Innovator’s Roadmap posts from Boston Children’s Hospital’s Innovation & Digital Health Accelerator (IDHA). Matt Murphy is Innovation Lead at IDHA.

We recently provided guidelines for selecting a platform and developing a Minimal Viable Product to take your digital health innovation beyond the prototype stage and create meaningful iterations. Once a Minimum Viable Product has been developed, numerous commercialization pathways are available, such as licensing an innovation to an existing company. But for many innovators, the best path may involve forming a startup company.

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7 digital health tips: Selecting a platform and developing a minimal viable product

digital health

Fifth in an ongoing series of Innovator’s Roadmap posts from Boston Children’s Hospital’s Innovation & Digital Health Accelerator (IDHA). Matt Murphy is Innovation Lead at IDHA.

We recently provided guidelines for developing prototypes of digital health products incorporating user-centered design and feedback from multiple sources. Let’s assume you’ve gone through multiple cycles of design updates, informed by your project goals and requirements, regulatory considerations and your long-term business or clinical strategy. Now, it’s time to select a technology platform and begin developing a fully functioning prototype of your innovation — your minimum viable product (MVP).

Below are some technical and tactical considerations to ensure your innovation’s long-term success and sustainability.

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Four prototyping strategies to test your healthcare innovation

digital health prototyping - paper sketch

Fourth in an ongoing series of Innovator’s Roadmap posts from Boston Children’s Hospital’s Innovation & Digital Health Accelerator (IDHA). Matt Murphy is Innovation Lead at IDHA.

We recently provided guidelines for designing for digital health, a process that requires a complete understanding of the pain point a technology aims to solve. So let’s assume you’ve defined your project goals, brainstormed solutions with critical stakeholders and written up the project requirements. What happens after this design process is complete?

Your next step is developing a prototype, a critical output of user-centered design.

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4 tactical steps to designing for digital health

design digital health

Third in an ongoing series of Innovator’s Roadmap posts from Boston Children’s Hospital’s Innovation & Digital Health Accelerator (IDHA). Matt Murphy is Innovation Lead at IDHA.

We recently provided market sizing guidelines for healthcare innovators — strategies to help you determine your innovation’s total number of potential users and your sales opportunities. Next, we’ll take you through our approach to designing digital health products.

The research and design phase is a critical step in the development and commercialization of digital health innovations. This phase is often referred to as user-centered design or human factors design. It requires a significant investment in understanding your users (including clinicians, clinical teams, patients and/or caregivers) and their pain points (problems they repeatedly experience) before developing a technology-based solution.

In our initial consultations with innovators at Boston Children’s Hospital, we spend only a small amount of time discussing end technology solutions. Instead, we seek to understand the intended users, their pain points and how they will interact with the innovation, including clinical, workflow and business considerations.

It’s market research taken a step further. We recommend you follow a specific four-step procedure to optimize the research and design phase.

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A healthcare Innovator’s Roadmap: 4 steps for developing a business model

healthcare innovation business plan

First in an on-going series of Innovator’s Roadmap posts from Boston Children’s Hospital’s Innovation & Digital Health Accelerator (IDHA). Matt Murphy is Innovation Lead at IDHA.

Seeing an idea go from the lab or clinic to the wider world is exciting. However, clinicians, researchers and administrators don’t always have the time or resources to take their innovations to the next step — that is, build them to scale. At Boston Children’s Hospital, the Innovation & Digital Health Accelerator (IDHA), comprised of 50+ researchers, business strategists and technologists, is dedicated to just that: We identify and vet high-priority health technology innovations at the hospital and provide the resources, funding and momentum to accelerate their development and commercialization.

To date, Boston Children’s has spun off more than 25 startup companies developed directly from clinical and research pain points. Some startups, like Neuromotion and Circulation, stand on their own. Others, including Epidemico, have been acquired by industry leaders. Through this experience, IDHA created the Innovator’s Roadmap – a comprehensive resource for taking ideas from concept to commercially available, impactful, economically sustainable products.

In this first installment, we look at the critical first step: understanding and justifying the business value of a technology or service by developing a business model.

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