Stories about: Information technology

8 winning innovations at Hacking Pediatrics

general hackersHacking Pediatrics, now in its third year, continues to experiment with its format. 2015’s “Mashup” had a greater focus on partnerships, curation and delivering value to innovators at Boston Children’s Hospital. The brunt of the idea pitching and team formation took place in advance, allowing the event, on November 14, to be collapsed into one day.

The Hacking Pediatrics team (Kate Donovan, Mike Docktor, Meg McCabe, Cassandra Bannos and Leila Amerling) brokered collaborations with a dozen industry partners such as Microsoft, Cerner, Box, CVS Health and Boston Scientific. Over the course of a hectic 12-hour day, they worked with 17 teams of Boston Children’s innovators and experts from partner organizations who presented their final ideas to a panel of judges.

In another change for 2015, the Hacking Pediatrics team issued nine awards — but no immediate prizes. This was meant to incentivize teams to continue to work and meet milestones to earn real rewards, like a $10,000 design prize offered up by design firm Mad*Pow.

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Mapping antibiotic resistance near you: ResistanceOpen

antibiotic resistance mapping ResistanceOpen

At the moment, it would appear the bacteria are winning. Antibiotic resistance is on the rise globally (in part because much of the public may not really understand how antibiotics work), threatening doctors’ ability to treat bacterial infections and potentially making surgery, chemotherapy and other medical procedures whose safety depends on antibiotic prophylaxis more risky.

Mapping antibiotic resistance — which bacteria are resistant to which drugs, and where — can help clinicians and public health officials decide how best to focus their control efforts. The challenge to date has been compiling resistance data in geographically useful ways.

“The data about antibiotic resistance are fragmented across laboratories and hospitals globally,” says Derek MacFadden, MD, a doctoral student at the Harvard T.H. Chan School of Public Health who is working with the HealthMap team in Boston Children’s Computational Health Informatics Program. “Most of the data that are available are very high level, so you can’t get an understanding of regional-level antibiotic resistance.”

This is where ResistanceOpen could come in handy. This new tool, launched by HealthMap team this week during the World Health Organization’s World Antibiotic Awareness Week, provides a window into regional and local antibiotic resistance patterns across the globe.

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IBM Watson Health and Medtronic: Where devices, data, and patient engagement meet

“When you’re dealing with a chronic disease like diabetes, 90 percent of medical care is done by the patients themselves,” says Jeff Ruiz, vice president of diabetes service and solutions at Medtronic. The time people with diabetes spend in the doctor’s office each year pales in comparison to the time they themselves spend managing their condition each and every day.

That’s why Medtronic, the world leader in diabetes management devices, is focused on patient engagement and turning real-time data into actionable insights. “You can provide all the best devices and medications, but it’s up to the patient at the end of the day,” said Ruiz, speaking on Monday during a panel discussion at the 2015 Boston Children’s Hospital Global Pediatric Innovation Summit + Awards.

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Aneesh Chopra: Five insights for innovators

In the mid-2000s, David Van Sickle, a researcher at the Centers for Disease Control and Prevention, had a hypothesis. He suspected asthma treatment might be overemphasizing direct patient intervention and underemphasizing broader environmental and health factors.

To test his hunch, Van Sickle enabled asthma inhalers with GPS technology and placed them in the hands of 1,000 people in Louisville, Kentucky. By tracking the time and location of asthma attacks and layering the results with open government data, Van Sickle discovered clusters of attacks in certain sections of the city — a finding that’s helping to clarify the link between asthma and environmental factors such as air quality.

According to Aneesh Chopra, cofounder of Hunch Analytics and the first-ever U.S. chief technology officer, Van Sickle — now the CEO of Propeller Health, a platform for respiratory health management — represents a new breed of health-care innovators who are using software and apps to draw insights from masses of data.

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Rock Health, Boston Children’s Hospital join to speed pediatric digital health startups

Bridget Duffy MDBoston Children’s Hospital and Rock Health, a venture fund dedicated to digital health, announced a strategic partnership aimed at accelerating pediatric health technologies during the hospital’s 2015 Global Pediatric Innovation Summit + Awards. Bridget Duffy, MD, is chair of Rock Health, chief Medical Officer of Vocera and co-founder of the Experience Innovation Network.

As a physician, entrepreneur, and especially as a parent, I am excited and inspired by a partnership between Rock Health and Boston Children’s Hospital to identify promising companies and cultivate emerging technologies focused on transforming pediatric care. Together, Rock Health and Boston Children’s Hospital will seed bigger ideas, accelerate adoption of new solutions, and massively change the way medicine is delivered to every child.

A global leader in pediatric clinical care, Boston Children’s Hospital will lend its expertise to support Rock Health’s portfolio and help shape the next generation of innovations. While Rock Health already has a proven track record with companies in this space, such as Kurbo Health, Cellscope and Kinsights, this close relationship with Boston Children’s will greatly accelerate the design and evaluation of new solutions, improving the health care experience for children and their caregivers.

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TriVox Health: improving care through shared online tracking

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Since we spoke with the founders of TriVox Health in 2014, their disease management program has taken off. The program began in Boston Children’s Hospital’s Division of Developmental Medicine as a way to more efficiently collect information on children’s ADHD symptoms from parents and teachers. It is now a user-friendly, web-based platform for tracking multiple conditions, incorporating medication confirmation, side effects reporting, disease symptom surveys and quality of life measures.

Vector sat down with founders Eric Fleegler, MD, MPH and Eugenia Chan, MD, MPH to learn about TriVox Health’s rapid growth over the past year, and what their plans are for the future.

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My work, my life, my innovations: Salim Afshar, DMD, MD

By the time oral and maxillofacial surgeon Salim Afshar, DMD, MD, was 29 years old, he had acquired medical and dental degrees from Harvard Medical School and Harvard School of Dental Medicine. Ever since, he has dedicated his life to community service and his surgical skills to improving community and global health.

An impassioned humanitarian, Afshar serves as one of the faculty members in the Program in Global Surgery and Social Change at Harvard Medical School. As an entrepreneur and innovator, he’s co-founded a health care software company that enables providers to engage and manage patients and their families around complex episodes of care.

“My whole orientation in life is around being of service — service to my patients, service to my community and service to my family,” Afshar says.

Hover over the icons in the photo above to learn more about Afshar and what keeps him going.

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Are tweets a good measure of patient experience and health care quality?

Twitter speech bubblesWhen it comes to gauging quality, we often turn to Twitter, Yelp, Angie’s List and other networks for instant feedback on pretty much any company, contractor or store we do business with.

In contrast, hospitals often rely on tools like the Hospital Consumer Assessment of Healthcare Providers and System (HCAHPS) survey, which gives voice to patients and their concerns about the care they receive. But a new study published in the journal BMJ Quality & Safety suggests social media have something to add to that.

Notes_title_for_overlay“The main problems with measuring patient experience by survey are the small numbers of people who respond to surveys and the lag time,” says Jared Hawkins, MMSc, PhD, of Boston Children’s Hospital’s Computational Health Informatics Program (CHIP). “It can take up to two years before survey data are released to the public. Given that social media data are close to real time, we wanted to see if we could capture this discussion and if the content is useful.”

Hawkins, with Boston Children’s chief innovation officer, John Brownstein, PhD, and their colleagues collected more than 400,000 public tweets directed at the Twitter handles of nearly 2,400 U.S. hospitals between 2012 and 2013. Using machine learning, natural language processing and manual curation, they tagged 34,735 patient experience tweets directed at 1,726 hospital-owned Twitter accounts.

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A banquet of tools for health tech innovators

Tools-Shutterstock-donatas1205-croppedWant to hack something in medicine? Vendors are increasingly eager to contribute their tools to problem-solving teams, like those who will gather November 14 for Boston Children’s Hospital’s Hacking Pediatrics. Seeing an array of tools presented at a showcase at Boston Children’s last week, I felt excited about the possibilities ahead.

Here are a few tools that can help innovators improve health care for patients, caregivers and providers.

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DNA diversity in the brain: Somatic mutations reveal a neuron’s history

neurons somatic mutations
Neurons are more like snowflakes–no two alike–than anyone realized.

Walt Whitman’s famous line, “I am large, I contain multitudes,” has gained a new level of biological relevance in neuroscience.

As we grow, our brain cells develop different genomes from one another, according to new research from Harvard Medical School and Boston Children’s Hospital. The study, published last week in Science, provides the most definitive evidence yet that somatic (post-conception) mutations exist in significant numbers in the brains of healthy people—about 1,500 in each of the neurons they sampled.

The finding confirms previous suspicions and lays the foundation for exploring the role of these non-inherited mutations in human development and disease. Already, the researchers have found evidence that the mutations occur more often in the genes a neuron uses most. And they been able to trace brain-cell lineages based on mutation patterns.

“This work is a proof of principle that if we had unlimited resources, we could actually decode the whole pattern of development of the human brain,” says co-senior investigator Christopher Walsh, MD, PhD, the HMS Bullard Professor of Pediatrics and Neurology and chief of the Division of Genetics and Genomics at Boston Children’s. “These mutations are durable memory for where a cell came from and what it has been up to. I believe this method will also tell us a lot about healthy and unhealthy aging as well as what makes our brains different from those of other animals.”

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